Laboratory Diagnosis of Tick-Borne Infections

Introduction

July 2010

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Our speaker for this program is Dr. Matthew Binnicker, Assistant Professor of Laboratory Medicine and Pathology, Director of the Infectious Diseases Serology Laboratory and Associate Director of the Mycology/Mycobacteriology Laboratory in the Division of Clinical Microbiology at Mayo Clinic. In Part 1, Dr. Binnicker will provide an overview and case studies of the conventional methods for detection and diagnosis of tick-borne infections. In Part 2, which is also posted, Dr. Bobbi Pritt discusses the molecular methods available for detection and diagnosis of tick-borne infections.

In this presentation, we’ll discuss the conventional laboratory methods for the diagnosis of tick-borne infections, with an emphasis on how serology should be used and interpreted in cases of suspected tick-borne disease.

Introduction

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Jump to section:

• Outline
• Patient Case 1
• Laboratory Workup
• Conventional Methods for Diagnosis of Ehrlichiosis and Anaplasmosis
• Conventional Methods for Diagnosis of Ehrlichiosis and Anaplasmosis
• Conventional Methods for Diagnosis of Ehrlichiosis and Anaplasmosis
• Typical Positive Result by IFA
• Conventional Methods for Diagnosis of Ehrlichiosis and Anaplasmosis
• Diagnostic Tests for HME and HGA
• Conventional Methods for Diagnosis of Ehrlichiosis and Anaplasmosis
• Conventional Methods for Diagnosis of Ehrlichiosis and Anaplasmosis
• Patient Case 2
• Giemsa-stained Preparation Slide
• Giemsa-stained Preparation Slide
• Conventional Methods for Diagnosis of Babesia
• Conventional Methods for Diagnosis of Babesia
• Conventional Methods for Diagnosis of Babesia
• Conventional Methods for Diagnosis of Babesia
• Conventional Methods for Diagnosis of Babesia
• Patient Case 3
• Lyme Disease - Diagnostic Approach
• Conventional Methods for Diagnosis of Lyme Disease
• Patient Case 3 (continued)
• Diagnosis of Lyme Disease
• Lyme Disease - Serologic Assays
• Lyme Disease - Serologic Assays
• Lyme Disease - Serologic Assays
• Patient Case 3 (continued)
• Lyme Disease - Serologic Assays
• Patient Case 3 (continued)
• Lyme Disease - Factors to Consider
• Conclusions
• References
• Questions?