Platelet Esoteric Testing
A Case Study
Unique Bone Marrow Findings in Patients with GPS
June 2010
Patients with gray platelet syndrome(GPS) may also develop bone marrow reticulin fibrosis, possibly due to premature release of alpha-granule contents. In bone marrow, megakaryocytes may show emperipolesis which stands for engulfing other blood cells into their cytoplasm of megakaryocytes.
Unique Bone Marrow Findings |
Jump to section:
- Introduction
- Bleeding and Thrombosing Diseases: 2010 Mayo Update
- Clinical Presentation
- Bleeding History - 1
- Bleeding History - 2
- Complete Blood Count (CBC)
- Peripheral Blood Smear
- Coagulation Studies
- Platelet Function Studies
- Differential Diagnosis ?
- Laboratory Approach to Qualitative Platelet Disorders
- Platelet Qualitative Disorders
- Laboratory Systemic Approach
- Macro-thrombocytopenia
- Flow Cytometry Studies
- Platelet Activity By Flow Cytometry
- Macro-thrombocytopenia
- Ultrastructure Studies Whole Mount
- Ultrastructure Studies Thin Sections
- Macro-thrombocytopenia
- Molecular Studies
- Final Diagnosis
- Global Prevalence of GPS
- GPS-Clinical Presentation
- Laboratory Findings
- Differential Diagnoses of Gray Platelets
- Unique Bone Marrow Findings in Patients with GPS
- Clinical Presentation
- Myelofibrosis
- Emperipolesis
- GPS-Treatment
- Summary
- Acknowledgment
- Bleeding and Thrombosing Diseases: 2010 Mayo Update
- Questions?
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