Platelet Esoteric Testing
A Case Study
Differential Diagnoses of Gray Platelets

June 2010
However, hypogranular or gray platelets can be seen in other acquired or congenital conditions. The acquired conditions include myelodysplastic syndrome(MDS) or myocardial infarction, and hypersplenism. The congenital conditions include alpha-delta granule deficiency, GATA-1 mutation associated platelet disorder, gray platelet syndrome, white platelet syndrome, Medich platelet disorder and Quebec platelet syndrome. Therefore, a systemic approach is needed to reach a final diagnosis.
Differential Diagnoses of Gray Platelets |
Jump to section:
- Introduction
- Bleeding and Thrombosing Diseases: 2010 Mayo Update
- Clinical Presentation
- Bleeding History - 1
- Bleeding History - 2
- Complete Blood Count (CBC)
- Peripheral Blood Smear
- Coagulation Studies
- Platelet Function Studies
- Differential Diagnosis ?
- Laboratory Approach to Qualitative Platelet Disorders
- Platelet Qualitative Disorders
- Laboratory Systemic Approach
- Macro-thrombocytopenia
- Flow Cytometry Studies
- Platelet Activity By Flow Cytometry
- Macro-thrombocytopenia
- Ultrastructure Studies Whole Mount
- Ultrastructure Studies Thin Sections
- Macro-thrombocytopenia
- Molecular Studies
- Final Diagnosis
- Global Prevalence of GPS
- GPS-Clinical Presentation
- Laboratory Findings
- Differential Diagnoses of Gray Platelets
- Unique Bone Marrow Findings in Patients with GPS
- Clinical Presentation
- Myelofibrosis
- Emperipolesis
- GPS-Treatment
- Summary
- Acknowledgment
- Bleeding and Thrombosing Diseases: 2010 Mayo Update
- Questions?


