Cerebrospinal Fluid Bacterial Antigen

Cases With and Without Classic Bacterial Meningitis-Causing Organisms and Number Missed by BAT and Gram Stain

May 2010

Classic meningitis-causing organisms were grown from cerebrospinal fluid culture in 29 of 42 cases. In 9 of the culture-negative cerebrospinal fluid cases, culture of blood or ear drainage yielded classic meningitis organisms. In the cases with positive cultures from cerebrospinal fluid, blood, or ear drainage, the results of bacterial antigen test and Gram stain were analyzed by organism type and are shown here. There were 22 Streptococcus pneumoniae cases, 6 of which were missed by bacterial antigen test, and 3 of which were missed by Gram stain. There were 7 group B streptococcus cases, 3 of which were missed by bacterial antigen test, and none of which were missed by Gram stain. There were 7 meningococcal cases, 3 of which were missed by bacterial antigen test, and 1 of which were missed by Gram stain. There were 2 Haemophilus influenzae type b cases, none of which were missed by bacterial antigen test, and 1 of which was missed by Gram stain.

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Jump to section:

• Introduction
• Bacterial Antigen Test (BAT)
• Bacterial Antigen Test (BAT)
• Study Overview
• Study Methods
• Study Methods
• Comparison of BAT and Gram Stain
• Cases With and Without Classic Bacterial Meningitis-Causing Organisms and Number Missed by BAT and Gram Stain
• Results
• Studies by Other Investigators
• Studies by Other Investigators
• Conclusions
• Acknowledgments
• References
• References
• Questions?