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Understanding Viral Load Assays for Cytomegalovirus and Epstein-Barr Virus


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Patients and Immunosuppression

Slide 3

March 2010

The context for our discussion is primarily transplant patients who, because of their state of immunosuppression, have an increased susceptibility to infections in general. I will be focusing the discussion today on CMV and EBV.

In broad terms, when considering the total risk of EBV or CMV infection, one must consider the net state of immunosuppression, including any immunosuppression drugs, antiviral drugs, and any cell growth drugs that the patient may be taking.

Transplant patients can be grouped into 2 main categories: recipients of solid organs and recipients of hematopoetic stem cells. It is important to understand that there are many details providing important points of differentiation within each group, but these considerations are outside the scope of this discussion.

Patients and Immunosuppression


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