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Kidney Stones

Update in Diagnosis and Management



Genetics and Environment

Slide 4

February 2010

This slide depicts the way that genes and environment both contribute to kidney stone disease. Important environmental factors include causes of insensible fluid loss, as well as the composition of the diet. How dietary components are absorbed and then excreted by the kidneys can be influenced by genetics. These processes in turn determine the overall urinary supersaturation. Other genetic factors likely influence how this supersaturation translates into kidney stone growth, such as the functional capacity of urinary inhibitors.

Genetics and Environment

 


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