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Prosthetic Joint Infection Diagnosis



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Slide 25

January 2010

The sensitivity of tissue and sonicate fluid culture was reduced in patients receiving antimicrobial therapy.  For tissue culture, the sensitivity decreased from 76.9% to 47.8% to 41.2% as the antimicrobial-free interval before surgery decreased from greater than 14 days, to 4 to 14 days, to 0 to 3 days, respectively.  For sonicate fluid culture, the sensitivity was 82.1%, 87.0%, and 58.8% for the same time intervals, respectively.  Sonicate fluid culture was more sensitive than tissue culture when antimicrobial agents were discontinued within 14 days before surgery (75% versus 45% respectively).

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