Prosthetic Joint Infection Diagnosis

Results Prosthetic Hip or Knee Infection

January 2010

252 subjects with aseptic implant failure and 79 with prosthetic joint infection were enrolled.
Sonicate fluid was not concentrated; 0.5 ml was plated on an anaerobic and aerobic sheep blood agar plate and incubated anaerobically and aerobically, respectively.  This slide shows the quantity (and type) of microorganisms detected by sonicate fluid culture.  Most of the prosthetic joint infection specimens yielded >100 colony forming units per plate, whereas most of the aseptic failure specimens yielded no growth or a small number of colonies.  A cutoff of 5 colony-forming units of the same organism was determined to most accurately differentiate aseptic failure from infection.

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Jump to section:

• Introduction
• Total Hip and Knee Replacement Procedures United States 1990-2006
• Body Diagram
• Prosthetic Hip and Knee Infections United States 1990-2004
• Surgical Management of Prosthetic Hip or Knee Infection
• Common Causes Hip and Knee Arthroplasty Infection
• Unusual Causes of Prosthetic Joint Infection³
• Diagram
• Criteria for Diagnosis of Prosthetic Joint Infection
• Prosthetic Joint Infection Clinical Presentation
• C-Reactive Protein Erythrocyte Sedimentation Rate
• C-Reactive Protein Erythrocyte Sedimentation Rate
• Images
• ¹⁸F-fluoro-2-deoxyglucose Positron Emission Tomography/Computed Tomography Increased Activity Around the Bone-Prosthesis Interface
• Synovial Fluid Leukocyte/Differential Prosthetic Knee
• Studies of Intrasurgical Frozen-Section Histopathologic Findings of Acute Inflammation in Prosthetic Joint Infection Diagnosis
• Prospective Vortexing/Sonication Clinical Study Hip or Knee Implants⁶
• Staphylococcus epidermidis Biofilm on Polycarbonate Coupons Scanning Electron Microscopy
• Periprosthetic Tissue and Sonicate Fluid Culture
• Prospective Vortexing/Sonication Clinical Study Hip or Knee Implants⁶
• Definition of Prosthetic Hip and Knee Infection
• Number of Microorganisms Detected by Sonicate Fluid Culture
• Results Prosthetic Hip or Knee Infection
• Effect of Preoperative Antimicrobial Therapy on Culture Sensitivity in Patients with Prosthetic Hip or Knee Infection
• Diagram
• Prospective Clinical Study Shoulder Implants
• Prospective Clinical Study Shoulder Implants
• Definition of Definite Prosthetic Shoulder Infection
• Prospective Clinical Study Shoulder Implants
• Shoulder Arthroplasty Infection
• Acknowledgments
• References
• Questions?
• Disclosure