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Prosthetic Joint Infection Diagnosis



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C-Reactive Protein Erythrocyte Sedimentation Rate

Slide 12

January 2010

In the absence of underlying inflammatory conditions, C-reactive protein is the most useful preoperative blood test.  Although C-reactive protein and erythrocyte sedimentation rate are both elevated after uncomplicated arthroplasty surgery, C-reactive protein returns to preoperative levels earlier than does the erythrocyte sedimentation rate.  We recently examined preoperative C-reactive protein and erythrocyte sedimentation rate in 582 patients with knee, hip or shoulder implant failure.  Both were statistically significantly higher in the groups with prosthetic knee or hip infection compared to those with aseptic implant failure.  However, in the shoulder implant group, the erythrocyte sedimentation rate was not significantly different in the groups with prosthetic shoulder infection versus aseptic shoulder implant failure, and the C-reactive protein was minimally elevated in the former compared to the latter group.

Erythrocyte Sedimentation Rate

 


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