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Red Cell Folate Testing

Unwarranted and Overutilized in the Era of Folic Acid Supplementation


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Differences Between Folate Immunoassays

Slide 9

November 2010

There are notable differences between results obtained for red cell and serum folate assays between manufacturers, which is not an uncommon occurrence for any unstandardized assay on the market. Bias between test methods and platforms may be as low as 10% and as high as 70%, despite similar claims of traceability, and occurs throughout the analytical range of the assays. Therefore, there is currently no one standard for folate measurement and values can vary significantly from one laboratory to the next because of method differences.

Differences Between Folate Immunoassays

 


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