Red Cell Folate Testing
Unwarranted and Overutilized in the Era of Folic Acid Supplementation
Equivalence of Serum and RBC Folate
November 2010
In addition to the documented analytical variables and assay quality issues, over the last decade there has been a growing body of literature demonstrating the equivalence of red cell and serum folate testing, in an effort to improve test utilization and reduce unnecessary spending.
Equivalence of Serum and RBC Folate |
Jump to section:
- Introduction
- Folate
- Folate
- Selected Food Sources of Folate and Folic Acid*
- Causes of Folate Deficiency
- Laboratory Diagnosis of Folate Deficiency
- Folate and Vitamin B12 Deficiency
- Quantitation of Folate: Methods
- Differences Between Folate Immunoassays
- Analytical Imprecision: RBC Folate (CAP Surveys)
- Equivalence of Serum and RBC Folate
- Modern Folate Deficiency is Rare
- Mayo RBC/Serum Folate Orders 1999-2009
- Conclusions
- Questions?


