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Analytical Issues Surrounding Troponin Assays


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Is CK-MB Needed Anymore?

Slide 14

October 2010

The question often arises if CK-MB is even needed anymore. It is well recognized and accepted that it does not provide any additional information over troponin even in the setting of suspected re-infarction (which is rare today), assessing infarct size, before or after percutaneous coronary intervention, or in end stage renal disease patients. The only time CK-MB should be ordered is if there are suspicious false-positive troponin T or I results (although these can usually be resolved with heterophile blocking tubes or dilution studies) or if troponin testing is simply unavailable. Medicare does not reimburse troponin and CK-MB testing performed simultaneously.

Is CK-MB Needed Anymore?


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