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Diagnostic Challenges of Celiac Disease


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Case 2: Symptomatic Malabsorption

Slide 4

June 2010

The second case. This is a case of a 58-year-old woman with diarrhea and a 6-month history of steatorrhea and bloating. She is anemic, she has lost over 25 pounds, and her endoscopic biopsy shows partial villous atrophy.

The next logical step would be:
1. To make a definite diagnosis of celiac disease at this point and start a gluten-free diet;
2. Do HLA testing;
3. Order gliadin antibody levels; or
4. Order a choice of a Comprehensive Celiac Disease Cascade or a Serology Cascade.

Case 2


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