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QuantiFERON-TB Gold In-Tube

Applications and Keys to Accurate Performance


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Conventional Diagnosis of Latent Tuberculosis Infection (LTBI)

Slide 3

November 2009

Conventionally, the diagnosis of latent tuberculosis, or LTBI, has been accomplished through the use of the tuberculin skin test, which you may also hear referred to as the intradermal Mantoux test or the PPD. This test was originally derived from Koch’s tuberculin, and was first described by Koch in 1890. The tuberculin skin test has been in routine use since 1910, making it one of the oldest diagnostic methods still in use today.

The tuberculin skin test is useful for the identification of individuals who are asymptomatic but infected, but is also routinely used when examining patients with active TB.

Conventional Diagnosis of LTBI


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