QuantiFERON-TB Gold In-Tube

QuantiFERON-TB Gold In-Tube Applications

November 2009

Now I’d like to turn our attention to the applications of QuantiFERON and also discuss the assay’s key performance characteristics. I think one of the major questions that clinicians and laboratorians are asking is “Can interferon gamma release assays, such as QuantiFERON, be used in place of the tuberculin skin test?”  In 2005, a panel of experts in the field of TB diagnostics, including members of the CDC, drafted a guidance document on the use and interpretation of QuantiFERON. In this document, the group concluded that QuantiFERON can be used in all circumstances in which the tuberculin skin test is used, including the following scenarios; contact investigations, evaluation of recent immigrants with a history of BCG vaccination, TB screening of health care workers, and serial evaluation for the diagnosis of TB infection.

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Jump to section:

• Introduction
• The Global Impact of Tuberculosis
• Conventional Diagnosis of Latent Tuberculosis Infection (LTBI)
• Limitations of TST
• Interferon Gamma Release Assays (IGRA): An Alternative to TST?
• QuantiFERON-TB Gold In-Tube
• QuantiFERON-TB Gold In-Tube, cont.
• QuantiFERON-TB Gold In-Tube, cont.
• QuantiFERON-TB Gold In-Tube Advantages over TST
• QuantiFERON-TB Gold In-Tube Limitations
• QuantiFERON-TB Gold In-Tube Applications
• QuantiFERON-TB Gold In-Tube Applications, cont.
• QuantiFERON-TB Gold In-Tube Applications, cont.
• QuantiFERON-TB Gold In-Tube Applications, cont.
• QuantiFERON-TB Gold In-Tube Applications, cont.
• QuantiFERON-TB Gold In-Tube Applications, cont.
• QuantiFERON-TB Gold In-Tube Applications, cont.
• QuantiFERON-TB Gold In-Tube Applications, cont.
• Information for Collection Sites Keys to Accurate Performance
• Blood Collection
• Blood Collection, cont.
• Blood Collection, cont.
• Blood Collection, cont.
• Mixing of Blood Collection Set
• Mixing of Blood Collection Set
• Storage and Incubation
• Storage and Incubation
• Incubation
• Centrifugation of Collection Tubes
• Shipping Specimens
• QuantiFERON-TB Gold In-Tube Conclusions
• Questions?