QuantiFERON-TB Gold In-Tube
Applications and Keys to Accurate Performance
QuantiFERON-TB Gold In-Tube Limitations

November 2009
Although there are significant advantages of QuantiFERON over conventional testing, there are also several limitations to this method. Despite QuantiFERON showing enhanced specificity, studies have shown that this method may still demonstrate cross-reactivity with some nontuberculous mycobacterial infections, including those caused by Mycobacterium kansasii, Mycobacterium szulgai and Mycobacterium marinum. A second limitation is the paucity of data for QuantiFERON in certain patient populations, including young children, immunocompromised patients, and pregnant women. Due to the lack of studies with these groups of patients, the interpretation of QuantiFERON results can be difficult, and future studies are needed.
Limitations |
Jump to section:
- Introduction
- The Global Impact of Tuberculosis
- Conventional Diagnosis of Latent Tuberculosis Infection (LTBI)
- Limitations of TST
- Interferon Gamma Release Assays (IGRA): An Alternative to TST?
- QuantiFERON-TB Gold In-Tube
- QuantiFERON-TB Gold In-Tube, cont.
- QuantiFERON-TB Gold In-Tube, cont.
- QuantiFERON-TB Gold In-Tube Advantages over TST
- QuantiFERON-TB Gold In-Tube Limitations
- QuantiFERON-TB Gold In-Tube Applications
- QuantiFERON-TB Gold In-Tube Applications, cont.
- QuantiFERON-TB Gold In-Tube Applications, cont.
- QuantiFERON-TB Gold In-Tube Applications, cont.
- QuantiFERON-TB Gold In-Tube Applications, cont.
- QuantiFERON-TB Gold In-Tube Applications, cont.
- QuantiFERON-TB Gold In-Tube Applications, cont.
- QuantiFERON-TB Gold In-Tube Applications, cont.
- Information for Collection Sites Keys to Accurate Performance
- Blood Collection
- Blood Collection, cont.
- Blood Collection, cont.
- Blood Collection, cont.
- Mixing of Blood Collection Set
- Mixing of Blood Collection Set
- Storage and Incubation
- Storage and Incubation
- Incubation
- Centrifugation of Collection Tubes
- Shipping Specimens
- QuantiFERON-TB Gold In-Tube Conclusions
- Questions?