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Biomarkers of Acute Renal Failure


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Towards a Kidney Troponin

Slide 5

August 2009

The biomarker field is fairly well developed in cardiology. Release of enzymes such as AST, CPK, and LDH were identified in the 1950s and 60s. These have been refined to include CPK MB and then troponin over the last several decades. Currently, additional biomarkers are being developed that may better identify subtle ongoing ischemia within the myocardium. In comparison, in nephrology, serum creatinine has remained the only real biomarker for many decades. To be fair, there are promising new biomarkers on the horizon, many of which I will discuss today, so this slide may need to be updated soon. The point remains, however, that we have a long way to go catch up to the cardiologists.

Towards a Kidney Troponin


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