Biomarkers of Acute Renal Failure
Leukocyte Cast

August 2009
This slide shows an example of a white blood cell or leukocyte cast. These are typically seen in ongoing kidney infection or pyelonephritis. They could also be seen in acute interstitial nephritis, in which case eosinophils might also be found in the cast.
Leukocyte Cast |
Jump to section:
- Introduction
- Acute Kidney Injury
- Common Causes of Acute
- Progression From Pre-renal to Acute Tubular Necrosis
- Towards a Kidney Troponin
- Origin of Formed Elements in Urinalysis
- Urinanalysis: A Traditional Biomarker of AKI
- Hyaline Casts
- Renal Epithelial Cell Cast
- Leukocyte Cast
- RBC Cast
- Pigmented Cast
- Granular Cast
- Other Helpful Indices
- Potential Sources of Urinary Biomarkers
- NGAL as a Biomarker
- Studies Support NGAL as a Biomarker of AKI in the Following Situations
- Mayo Renal Laboratory Urinary NGAL Normals
- Normal Urinary NGAL Levels are Not Dependent on Age, but are Higher in Women than Men
- Ongoing Mayo Clinic Clinical Validation Study
- Ongoing Mayo Clinic Clinical Validation Study: Preliminary Results
- Study
- Other Potential Markers on the Horizon
- Mayo Clinic Goals
- Conclusions
- References
- Questions?


