Autoantibody Profiles of Myasthenia Gravis, Thymoma & Lambert-Eaton Myasthenic Syndrome
What are MG and LES?
July 2009
Myasthenia Gravis. In this disorder, antibodies bind to the acetylcholine receptors in the muscle membrane. If this occurs, this impairs the passage of sodium and potassium ions passing through the ACh-gated channels that depolarize the muscle end-plate. In Lambert-Eaton syndrome, the antibodies bind to voltage-gated calcium channels in nerve terminals that regulate acetylcholine release.
What are MG and LES? |
Jump to section:
- Introduction
- Serological Diagnostic Algorithms
- 'Hot Topic' Points
- What are MG and LES?
- What are MG and LES?
- MG: Clinical Diagnosis
- MG: Neoplastic Accompaniments
- LES: Clinical Diagnosis
- LES: Electromyography (EMG) Findings
- LES: Neoplastic Accompaniments
- Autoantibodies Aiding MG Diagnosis
- Autoantibodies Aiding MG Diagnosis
- Single Assay Detects AChR Modulating and AChR Blocking Antibodies
- Serum AChR Modulating Antibody Values and Interpretation
- Reasons to Discontinue Testing for AChR Blocking Antibody
- Striational Antibodies
- Autoantibodies Detected in MG Patients with Thymoma
- Autoantibodies Aiding the Diagnosis of LES
- Autoantibodies Aiding the Diagnosis of LES
- Myasthenia Gravis: Adult Diagnostic Algorithm
- Myasthenia Gravis: Pediatric Diagnostic Algorithm
- Myasthenia Gravis: Thymoma Diagnostic Algorithm
- Myasthenia Gravis/Lambert Eaton Syndrome Diagnostic Algorithm
- Summary
- Questions?
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