Autoantibody Profiles of Myasthenia Gravis, Thymoma & Lambert-Eaton Myasthenic Syndrome
Myasthenia Gravis/Lambert Eaton Syndrome Diagnostic Algorithm
July 2009
For the myasthenia gravis and Lambert-Eaton syndrome diagnostic algorithm, this is generally undertaken where there is some clinical uncertainly as to the diagnosis. Testing always consists of antibodies tests for Lambert-Eaton syndrome consisting of the P/Q-type calcium channel antibody, N-type calcium channel antibody, and then antibody tests pertaining to myasthenia gravis consisting of acetylcholine receptor binding antibody, modulating antibodies, and striational antibody. Again, if the acetylcholine receptor modulating antibodies loss is >90% and the striational antibody is present, testing is automatically reflexed to the ganglionic acetylcholine receptor antibody and CRMP-5-IgG testing.
Myasthenia Gravis/Lambert Eaton Syndrome Diagnostic Algorithm |
Jump to section:
- Introduction
- Serological Diagnostic Algorithms
- 'Hot Topic' Points
- What are MG and LES?
- What are MG and LES?
- MG: Clinical Diagnosis
- MG: Neoplastic Accompaniments
- LES: Clinical Diagnosis
- LES: Electromyography (EMG) Findings
- LES: Neoplastic Accompaniments
- Autoantibodies Aiding MG Diagnosis
- Autoantibodies Aiding MG Diagnosis
- Single Assay Detects AChR Modulating and AChR Blocking Antibodies
- Serum AChR Modulating Antibody Values and Interpretation
- Reasons to Discontinue Testing for AChR Blocking Antibody
- Striational Antibodies
- Autoantibodies Detected in MG Patients with Thymoma
- Autoantibodies Aiding the Diagnosis of LES
- Autoantibodies Aiding the Diagnosis of LES
- Myasthenia Gravis: Adult Diagnostic Algorithm
- Myasthenia Gravis: Pediatric Diagnostic Algorithm
- Myasthenia Gravis: Thymoma Diagnostic Algorithm
- Myasthenia Gravis/Lambert Eaton Syndrome Diagnostic Algorithm
- Summary
- Questions?
External
link
PDF
document
Excel
document
Word
document