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Autoantibody Profiles of Myasthenia Gravis, Thymoma & Lambert-Eaton Myasthenic Syndrome

Autoantibodies Detected in MG Patients with Thymoma

Slide 17

July 2009

These and other antibody tests are positive in patients with thymoma, as well as myasthenia gravis. The acetylcholine receptor binding antibody is present in 100% of patients with thymoma. The acetylcholine receptor modulating antibody is present in almost all patients - 99% of patients with thymoma. Striational antibodies are present in 76% of patients with thymoma. And then a variety of other neural-specific antibodies are present in 43% of patients with thymoma. This includes the voltage-gated potassium channel antibody, CRMP-5 IgG, the ganglionic acetylcholine receptor antibody, and GAD65 antibody, which is the commonest neural antibody detected in patients with thymoma.

MG Patients with Thymoma


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