Autoantibody Profiles of Myasthenia Gravis, Thymoma & Lambert-Eaton Myasthenic Syndrome
Autoantibodies Aiding MG Diagnosis
July 2009
So what autoantibody tests aid the diagnosis of myasthenia gravis? Well, first of all, the acetylcholine receptor binding antibody. This can distinguish myasthenia gravis of an acquired type from congenital myasthenia gravis. The presence of this antibody will also raise the question of subclinical myasthenia gravis in thymoma patients where no weakness has been detected. The antibody is also detected in a few patients who have other autoimmune neurological disorders, including Lambert-Eaton syndrome in 10% and, rarely but significantly, in patients with peripheral neuropathies, encephalopathies, and radiculomyelopathies.
Autoantibodies Aiding MG Diagnosis |
Jump to section:
- Introduction
- Serological Diagnostic Algorithms
- 'Hot Topic' Points
- What are MG and LES?
- What are MG and LES?
- MG: Clinical Diagnosis
- MG: Neoplastic Accompaniments
- LES: Clinical Diagnosis
- LES: Electromyography (EMG) Findings
- LES: Neoplastic Accompaniments
- Autoantibodies Aiding MG Diagnosis
- Autoantibodies Aiding MG Diagnosis
- Single Assay Detects AChR Modulating and AChR Blocking Antibodies
- Serum AChR Modulating Antibody Values and Interpretation
- Reasons to Discontinue Testing for AChR Blocking Antibody
- Striational Antibodies
- Autoantibodies Detected in MG Patients with Thymoma
- Autoantibodies Aiding the Diagnosis of LES
- Autoantibodies Aiding the Diagnosis of LES
- Myasthenia Gravis: Adult Diagnostic Algorithm
- Myasthenia Gravis: Pediatric Diagnostic Algorithm
- Myasthenia Gravis: Thymoma Diagnostic Algorithm
- Myasthenia Gravis/Lambert Eaton Syndrome Diagnostic Algorithm
- Summary
- Questions?
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