Hemoglobin A1c and the Estimated Average Glucose
Hemoglobin A1c (HbA1c)
July 2009
Hemoglobin A1c is another important analyte for monitoring the progress of a diabetic over time. Adult hemoglobin is comprised mainly of hemoglobin A, and to a lesser extent hemoglobin A2 and fetal hemoglobin in hematologically normal individuals. Hemoglobin A1c should not be confused with hemoglobin A1, as hemoglobin A1 consists of hemoglobin A1a, A1b and A1c; however, hemoglobin A1c makes up approximately 80% of hemoglobin A1. Hemoglobin A1c is also referred to as glycated hemoglobin, glycohemoglobins, and fast hemoglobin, due to its migration pattern on electrophoresis.
Hemoglobin A1c (HbA1c) |
Jump to section:
- Introduction
- US Diabetes Prevalence
- Diagnosis of Diabetes
- Categories of Glucose Values
- Importance of Diagnosis
- Role of the Laboratory
- Fasting Plasma Glucose
- Fasting Plasma Glucose
- Hemoglobin A1c (HbA1c)
- Glycation
- HbA1c Concentration
- Diabetes Treatment Goals
- HbA1c Methods
- Hemoglobin Variants
- Hemoglobinopathies
- Reporting HbA1c as an eAG
- HbA1c and Average Glucose
- Derivation of Estimated Average Glucose (eAG)
- HbA1c/eAG Table
- Limitations
- Endorsement of eAG
- HbA1c for Diagnosis of Diabetes
- Disadvantages
- International Expert Committee Report on the Role of the A1c Assay in the Diagnosis of Diabetes
- HbA1c at Mayo Clinic
- Conclusions
- Questions?
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