Hemoglobin A1c and the Estimated Average Glucose
Fasting Plasma Glucose

July 2009
Measurement of the fasting plasma glucose has several advantages; glucose is easy to measure in terms of technical intervention and it is widely available on automated instruments. Only one specimen is needed, as opposed to timed specimens with the oral glucose tolerance test. In addition there is a single cutoff used for diagnosis, 126 mg/dL. It should also be mentioned that point of care analyzers are not sufficiently precise enough to be used for diagnosis of diabetes and should not be used for this purpose.
Fasting Plasma Glucose |
Jump to section:
- Introduction
- US Diabetes Prevalence
- Diagnosis of Diabetes
- Categories of Glucose Values
- Importance of Diagnosis
- Role of the Laboratory
- Fasting Plasma Glucose
- Fasting Plasma Glucose
- Hemoglobin A1c (HbA1c)
- Glycation
- HbA1c Concentration
- Diabetes Treatment Goals
- HbA1c Methods
- Hemoglobin Variants
- Hemoglobinopathies
- Reporting HbA1c as an eAG
- HbA1c and Average Glucose
- Derivation of Estimated Average Glucose (eAG)
- HbA1c/eAG Table
- Limitations
- Endorsement of eAG
- HbA1c for Diagnosis of Diabetes
- Disadvantages
- International Expert Committee Report on the Role of the A1c Assay in the Diagnosis of Diabetes
- HbA1c at Mayo Clinic
- Conclusions
- Questions?


