Hemoglobin A1c and the Estimated Average Glucose
Importance of Diagnosis
July 2009
Previous research trial groups, including the Diabetes Control and Complications Trial (DCCT) and the United Kingdom Prospective Diabetes Study (UKPDS) both demonstrated a strong relationship between the level of plasma glucose control for both type 1 and type 2 diabetes and the risk of retinal, renal, and neurological complications. Therefore, the critical importance on diagnosis of diabetes relates to the high prevalence of long term medical complications in diabetics, which in turn can have devastating effects on both the patients and place a burden on the health care system. It is estimated that one quarter of diabetics manifest complications at the time of diagnosis and there is an approximate 7 year gap between the onset of diabetes and clinical diagnosis.
Importance of Diagnosis |
Jump to section:
- Introduction
- US Diabetes Prevalence
- Diagnosis of Diabetes
- Categories of Glucose Values
- Importance of Diagnosis
- Role of the Laboratory
- Fasting Plasma Glucose
- Fasting Plasma Glucose
- Hemoglobin A1c (HbA1c)
- Glycation
- HbA1c Concentration
- Diabetes Treatment Goals
- HbA1c Methods
- Hemoglobin Variants
- Hemoglobinopathies
- Reporting HbA1c as an eAG
- HbA1c and Average Glucose
- Derivation of Estimated Average Glucose (eAG)
- HbA1c/eAG Table
- Limitations
- Endorsement of eAG
- HbA1c for Diagnosis of Diabetes
- Disadvantages
- International Expert Committee Report on the Role of the A1c Assay in the Diagnosis of Diabetes
- HbA1c at Mayo Clinic
- Conclusions
- Questions?
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