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Hemoglobin A1c and the Estimated Average Glucose



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Slide 23

July 2009

Some arguments against using HbA1c for diagnosis of diabetes include the limited number of studies which have been performed thus far to derive an adequate cutoff.  There are other conditions which alter HbA1c values including the presence of variants, uremia, transfusions, and anemias.  Some would also argue there are analytical issues which remain unresolved.  HbA1c is also a more expensive analyte to measure in the laboratory than glucose.

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