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Hemoglobin A1c and the Estimated Average Glucose



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HbA1c for Diagnosis of Diabetes

Slide 22

July 2009

In addition to reporting the eAG, hemoglobin A1c has also been targeted for a potential role in the diagnosis of diabetes.  The advantages to using HbA1c include that it gives a measurement of chronic hyperglycemia, based on the individuals red blood cell (RBC) lifespan.  The standardization efforts from the National Glycohemoglobin Standardization Program have been largely successful and the accuracy of HbA1c is closely monitored by manufacturers and laboratories.  No fasting is necessary to measure HbA1c and there is very low intraindividual variability with a CV of <2%.  In addition it would be a single test which could be used for both diagnosis and monitoring of diabetes.

HbA1c for Diagnosis of Diabetes

 


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