Hemoglobin A1c and the Estimated Average Glucose
US Diabetes Prevalence

July 2009
Diabetes is currently the seventh leading cause of death in the developed world. The American Diabetes Association defines diabetes as a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. In the United States, it is estimated from recent statistics that 23.6 million people have diabetes. Approximately 18 million of those individuals are diagnosed with diabetes, with type 1 diabetes accounting for 5-10% of cases and type 2 diabetes accounting for the majority of newly diagnosed patients. However, it is recognized that there are still 5-6 million individuals who remain undiagnosed and potentially at risk for premature development of micro and macrovascular complications.
US Diabetes Prevalence |
Jump to section:
- Introduction
- US Diabetes Prevalence
- Diagnosis of Diabetes
- Categories of Glucose Values
- Importance of Diagnosis
- Role of the Laboratory
- Fasting Plasma Glucose
- Fasting Plasma Glucose
- Hemoglobin A1c (HbA1c)
- Glycation
- HbA1c Concentration
- Diabetes Treatment Goals
- HbA1c Methods
- Hemoglobin Variants
- Hemoglobinopathies
- Reporting HbA1c as an eAG
- HbA1c and Average Glucose
- Derivation of Estimated Average Glucose (eAG)
- HbA1c/eAG Table
- Limitations
- Endorsement of eAG
- HbA1c for Diagnosis of Diabetes
- Disadvantages
- International Expert Committee Report on the Role of the A1c Assay in the Diagnosis of Diabetes
- HbA1c at Mayo Clinic
- Conclusions
- Questions?


