Hemoglobin A1c and the Estimated Average Glucose
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Introduction
July 2009
Welcome to Mayo Medical Laboratories' Hot Topics. These presentations provide short discussion of current topics and may be helpful to you in your practice.
Our presenter for this program is Amy K. Saenger, PhD, Director of the Central Clinical Laboratory in the Department of Laboratory Medicine & Pathology at Mayo Clinic in Rochester, Minnesota. Dr. Saenger will provide an overview of the diagnosis of diabetes and monitoring of the diabetic patient and discuss the advantages and disadvantages of hemoglobin A1c and fasting plasma glucose testing. She will define newly released recommendations from the American Diabetes Association and discuss the use and reporting of the estimated average glucose.
I will be discussing hemoglobin A1c testing and reporting of the estimated average glucose. This is a subject that has received much attention in both the clinical and laboratory realm due to the fact that there are major implications for measuring an accurate and precise HbA1c.
Introduction |
Jump to section:
- US Diabetes Prevalence
- Diagnosis of Diabetes
- Categories of Glucose Values
- Importance of Diagnosis
- Role of the Laboratory
- Fasting Plasma Glucose
- Fasting Plasma Glucose
- Hemoglobin A1c (HbA1c)
- Glycation
- HbA1c Concentration
- Diabetes Treatment Goals
- HbA1c Methods
- Hemoglobin Variants
- Hemoglobinopathies
- Reporting HbA1c as an eAG
- HbA1c and Average Glucose
- Derivation of Estimated Average Glucose (eAG)
- HbA1c/eAG Table
- Limitations
- Endorsement of eAG
- HbA1c for Diagnosis of Diabetes
- Disadvantages
- International Expert Committee Report on the Role of the A1c Assay in the Diagnosis of Diabetes
- HbA1c at Mayo Clinic
- Conclusions
- Questions?
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