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Uses and Limitations of Transcutaneous Bilirubin Measurement


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Slide 3

June 2009

We know that normal bilirubin levels increase during the first week of newborn life.  Common reasons for this include: Shortened lifespan and increased fragility of the newborn’s RBCs; Immaturity of the liver conjugation system; Increased reabsorption of bilirubin via the enterohepatic circulatory system; and other factors.  Bilirubin at low levels may be an antioxidant and protective but at extreme levels it can cause damage to the brain of the neonate.



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