Uses and Limitations of Transcutaneous Bilirubin Measurement

Conclusions

June 2009

In conclusion we found that transcutaneous bilirubin systematically overestimates serum bilirubin as it is measured at Mayo.  This finding is different from what has been described in previous studies.  The relationship between transcutaneous and serum bilirubin will be different in each institution.  We studied many clinical and laboratory variables that could have potentially affected the relationship between transcutaneous and serum bilirubin.  We found that only laboratory variables such as serum bilirubin method and collection container had any impact.  Because the relationship between transcutaneous and laboratory bilirubin will likely vary by institution, the utility of transcutaneous bilirubin screening will also vary by health care setting.

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• Introduction
• Outline
• Introduction
• Kernicterus
• Historical Information
• Focus of the Guideline
• Key Elements to the Recommendation
• Key Elements to the Recommendation, cont.
• Mayo Study of TcB
• Mayo Study of TcB, cont.
• Mayo Study of TcB: TcB vs. diazo TsB
• Mayo Study of TcB: TcB vs Vitros TsB
• Mayo Study of TcB
• Mayo Study of TcB, cont.
• Mayo Study of TcB, cont.
• Mayo Study of TcB, cont.
• Conclusions
• Conclusions, cont.
• References
• Questions?