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Uses and Limitations of Transcutaneous Bilirubin Measurement



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Mayo Study of TcB

Slide 13

June 2009

The major question we wanted to answer was whether transcutaneous bilirubin, along with postnatal age in hours, could be used to predict the risk of potentially dangerous serum bilirubin values.  To do this, we took each transcutaneous value, along with the infant’s postnatal age in hours, and plotted that in the conventional Bhutani nomogram used to interpret serum bilirubin values in our practice.  That nomogram uses bilirubin value and postnatal age in hours to divide risk into four zones: low, low-intermediate risk, high-intermediate, and high risk.  For the purposes of this talk, we will assume that both low and low-intermediate zones represent low-risk infants; and both high and high-intermediate zones represent high-risk infants.  We then calculated the sensitivity and specificity of a high-risk transcutaneous value predicting a high-risk serum value from the same infant.

Mayo Study of TcB

 


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