Uses and Limitations of Transcutaneous Bilirubin Measurement

Mayo Study of TcB: TcB vs Vitros TsB

June 2009

This is a Bland-Altmann plot showing the difference between transcutaneous and Vitros serum bilirubin, on the y-axis, vs. the mean of transcutaneous and serum bilirubin on the x-axis.  Again the relationship between transcutaneous and serum bilirubin is relatively constant across the range of bilirubin values encountered, but the median bias is significantly less at 1.3 mg/dL.  We can see from this data that the particular laboratory bilirubin method used is a major determinant of the relationship between transcutaneous and serum bilirubin.

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TcB vs Vitros TsB

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• Introduction
• Outline
• Introduction
• Kernicterus
• Historical Information
• Focus of the Guideline
• Key Elements to the Recommendation
• Key Elements to the Recommendation, cont.
• Mayo Study of TcB
• Mayo Study of TcB, cont.
• Mayo Study of TcB: TcB vs. diazo TsB
• Mayo Study of TcB: TcB vs Vitros TsB
• Mayo Study of TcB
• Mayo Study of TcB, cont.
• Mayo Study of TcB, cont.
• Mayo Study of TcB, cont.
• Conclusions
• Conclusions, cont.
• References
• Questions?