Uses and Limitations of Transcutaneous Bilirubin Measurement

Mayo Study of TcB: TcB vs. diazo TsB

June 2009

This is a Bland-Altmann plot showing the difference between transcutaneous and diazo serum bilirubin, on the y-axis, vs. the mean of transcutaneous and serum bilirubin on the x-axis.  On average transcutaneous bilirubin was significantly higher than diazo serum bilirubin, with a median bias of 2.0 mg/dL.  The relationship between transcutaneous and serum bilirubin does not appear to change much over the range of bilirubin levels encountered--suggesting a relatively constant bias between transcutaneous and serum bilirubin.

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TcB vs. diazo TsB

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• Introduction
• Outline
• Introduction
• Kernicterus
• Historical Information
• Focus of the Guideline
• Key Elements to the Recommendation
• Key Elements to the Recommendation, cont.
• Mayo Study of TcB
• Mayo Study of TcB, cont.
• Mayo Study of TcB: TcB vs. diazo TsB
• Mayo Study of TcB: TcB vs Vitros TsB
• Mayo Study of TcB
• Mayo Study of TcB, cont.
• Mayo Study of TcB, cont.
• Mayo Study of TcB, cont.
• Conclusions
• Conclusions, cont.
• References
• Questions?