Optimizing Busulfan Pharmacokinetic Testing

Example: A Typical Busulfan Curve, cont.

June 2009

Putting it all together, then, the two-hour intravenous infusion and the four-hour series of post-infusion samples are integrated together to determine the 6-hour Area Under the Curve.

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Example, cont.

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Jump to section:

• Introduction
• Busulfan
• Busulfan Pharmacokinetics
• Example: A Typical Busulfan Curve
• Example: A Typical Busulfan Curve, cont.
• Example: A Typical Busulfan Curve, cont.
• Measuring Drug Exposure
• #83188 Busulfan, Intravenous Dose, Area Under the Curve (AUC), Plasma
• Busulfan Patient Information Sheet
• Making Sure You Get Results
• Atypical Curve
• Atypical Curve, cont.
• Atypical Curve, cont.
• Atypical Curve, cont.
• Atypical Curve, cont.
• Atypical Curve, cont.
• The Problem With Atypical Curves
• Summary
• Questions?