Optimizing Busulfan Pharmacokinetic Testing

Atypical Curve, cont.

June 2009

… which sample or samples are the source of the atypical curve.  For example, what if the first two samples were accidentally switched? If this were the case, the “corrected” results would look like this…

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Atypical Curve, cont.

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Jump to section:

• Introduction
• Busulfan
• Busulfan Pharmacokinetics
• Example: A Typical Busulfan Curve
• Example: A Typical Busulfan Curve, cont.
• Example: A Typical Busulfan Curve, cont.
• Measuring Drug Exposure
• #83188 Busulfan, Intravenous Dose, Area Under the Curve (AUC), Plasma
• Busulfan Patient Information Sheet
• Making Sure You Get Results
• Atypical Curve
• Atypical Curve, cont.
• Atypical Curve, cont.
• Atypical Curve, cont.
• Atypical Curve, cont.
• Atypical Curve, cont.
• The Problem With Atypical Curves
• Summary
• Questions?