DNA Testing - The Next Generation
High Throughput, High Content Technologies
SOLiD System - Overview
May 2009
What’s been accomplished with the Illumina Machine? The very first person of Chinese ethnicity from Han ethnicity: Xinhua sequence; the first person of African descent: the Yaruba sequence. And the cost to sequence your genome last April was $50,000. My advice would be to wait a few months because it’s just going to cost less. The first upgrade of the genome sequencer originally it could do 1 GB in three days; it’s up to 3GBs. But in April there was an 8 GB run and today, I have heard of runs over 20 GBs per run.
SOLiD System - Overview |
Jump to section:
- Introduction
- The Human Genome Project
- ABI 3700 Machine
- Celera Genomics
- Greatest Impact of the Human Genome Project
- Technological Advances
- Process Overview
- One Fragment = One Bead = One Read
- Complete Workflow
- Capability of This Machine
- What's Been Accomplished with the 454?
- Illumina Genome Analyzer
- Genome Analyzer Workflow
- Flow Cell Preparation
- Generate Samples
- Raw Data is Images
- Sequence Construction
- What's Been Accomplished with the Illumina Machine?
- SOLiD System - Overview
- SOLiD System 2.0 - Launch May 2008
- SOLiD System Summary Overview
- Higher Accuracy - New Probe Mix 1,2 Probes (Version 2)
- Higher Accuracy - New Probe Mix 1,2 Probes (Version 2)
- Sequential Rounds of Sequencing 1,2 Probes (Version 2)
- So, What Can You Do with a NextGen Sequencer?
- Whole Genomes
- Detecting Rare Mutations
- Mate-pair Reads
- Hybrid Selection
- Bar Coding
- Clinical Diagnostics
- Next-NextGen?
- Center for Individualized Medicine (CIM)
- Generating a Data Source
- Capabilities Grow Exponentially
- So, What's Coming?
- Building the Infrastructure for NextGen (and Beyond) Sequencing
- Acknowledgments
- Questions?
External
link
PDF
document
Excel
document
Word
document