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Thyroid Function Testing: A Brief Update

Regulation of Thyroid Hormone Secretion

Slide 3

April 2009

Just to remind ourselves briefly about thyroid function and its regulation, it’s a typical and classical negative-feedback endocrine regulation system. The pituitary gland secretes thyroid-stimulating hormone, or TSH for short, which in turn interacts with the thyroid gland and makes it produce increased amounts of thyroxin, also known as T4 for short, and triiodothyronine, also known as T3 for short. Both of those provide negative feedback on the hypothalamus and the pituitary gland, and assay levels increase the levels of TSH downregulated, a classical thermostat.

Regulation of Hormone Secretion


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