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Middleware and the Clinical Hematology Laboratory



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Verification of the Differential: Where?

Slide 6

February 2009

Verification of the differential count can occur at any one of or combination of three steps.  Certainly the modern hematology instrument can either trap or auto-verify results based on quantitative flags that are usually set by the laboratory and qualitative flags that are established by the manufacturer and usually based on abnormal light scatter or other qualitative aspects determined by the instrument itself.  The LIS may also have the ability to apply autoverification rules.  This is dependent on the particular system you have and its rule writing capabilities.  Pushing the software support back to your LIS group will make it easier for the laboratory to meet regulatory requirements and it will also help provide necessary IT support and backup. In the laboratory the differential may be verified by either a technologist directly or with the use of middleware.  Middleware can be acquired from either instrument manufacturers or software vendors and should be capable of incorporating data from both the instrument as well as demographic and laboratory data from the LIS into a rule based approach.  It is critical when choosing and implementing a middleware solution, to bring that middleware vendor, the instrument manufacturer, and local LIS resources together to understand the necessary interfaces and more importantly, the limitations of all systems involved.  Again any combination of these three steps may be involved in the verification of the differential count.

Verification of the Differential: Where?

 


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