Diagnosis and Classification of Amyloidosis
Slide Images
December 2009
This is a duodenal biopsy specimen showing subtle amyloid deposition in the basal lamina of duodenal glands. In the upper left panel, Congo red stain gives pale orange-red reactivity with the amyloid deposits. In the upper right panel, under polarized light the deposits show characteristic apple-green birefringence. Similarly immunohistochemistry for serum amyloid P component (SAP) labels the amyloid deposited in the basal lamina of the glands. By electron microscopy (EM), the amyloid is composed of nonbranching fibrils.
Slide Images |
Jump to section:
- Introduction
- Amyloidosis
- Diagnosis1
- Slide Images
- Subtypes: Historical Context
- Subtypes2
- Subtyping
- Subtyping
- Subtyping in Tissues
- Mass Spectrometry-Based Proteomic Analysis of Amyloidosis
- Protein Extraction
- Fragmented Peptides
- Mass/charge of Daughter Ions Measured
- Bioinformatics
- Case History 1
- Bone Marrow Biopsy Image
- Flow Cytometry Immunophenotyping
- Bone Marrow Image
- Congo Red-Positive Slide Image
- Immunohistochemistry Slide Images
- Microdissection
- MS-Based Proteomic Analysis
- Diagnosis
- Case History 2
- Mass Spectrometry Results in 50 Cases of Amyloidosis3
- Summary: Diagnosis
- Summary: Classification
- References
- Questions?
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