Diagnosis and Classification of Amyloidosis
Diagnosis
December 2009
Therefore this patient has CLL and ATTR amyloidosis. No mutations were identified in the TTR gene consistent with age-related or senile ATTR. The patient is being observed with regards to CLL and receiving supportive treatment for cardiac amyloidosis. If a diagnosis of AL amyloidosis was made based on equivocal immunohistochemistry results, the patient may have received unnecessary treatment for the underlying lymphoproliferative disorder.
Diagnosis |
Jump to section:
- Introduction
- Amyloidosis
- Diagnosis1
- Slide Images
- Subtypes: Historical Context
- Subtypes2
- Subtyping
- Subtyping
- Subtyping in Tissues
- Mass Spectrometry-Based Proteomic Analysis of Amyloidosis
- Protein Extraction
- Fragmented Peptides
- Mass/charge of Daughter Ions Measured
- Bioinformatics
- Case History 1
- Bone Marrow Biopsy Image
- Flow Cytometry Immunophenotyping
- Bone Marrow Image
- Congo Red-Positive Slide Image
- Immunohistochemistry Slide Images
- Microdissection
- MS-Based Proteomic Analysis
- Diagnosis
- Case History 2
- Mass Spectrometry Results in 50 Cases of Amyloidosis3
- Summary: Diagnosis
- Summary: Classification
- References
- Questions?