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Diagnosis and Classification of Amyloidosis


Slide 23

December 2009

Therefore this patient has CLL and ATTR amyloidosis. No mutations were identified in the TTR gene consistent with age-related or senile ATTR. The patient is being observed with regards to CLL and receiving supportive treatment for cardiac amyloidosis. If a diagnosis of AL amyloidosis was made based on equivocal immunohistochemistry results, the patient may have received unnecessary treatment for the underlying lymphoproliferative disorder.



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