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Diagnosis and Classification of Amyloidosis

Case History 1

Slide 15

December 2009

I will now discuss two cases where mass spectrometry-based proteomic analysis was diagnostic. The first case was a 74-year-old male who presented with a long history of CLL and symptoms and signs such as carpal tunnel syndrome and restrictive cardiomyopathy, suggestive of systemic amyloidosis. In 2009, a bone marrow biopsy was performed and at that point, the patient had elevated lambda free light chain levels.

Case History 1


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