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Monitoring Monoclonal Gammopathies

Serum Protein Electrophoresis and Immunofixation Electrophoresis

Slide 4

November 2009

On this next slide is an example of a measurable serum M-spike. The upper portion of the figure is a serum protein electrophoresis and immunofixation electrophoresis of serum from a normal donor. The lower portion is from a patient with multiple myeloma. You can see that this patient has a monoclonal IgG kappa protein from the IFE or immunofixation electrophoresis gel and that the PEL or protein electrophoresis scan quantitates the M-spike as 3.8 g/dL.



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