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PSA Standardization

Recommendations for Screening

Slide 5

October 2009

Several clinical groups have advocated the benefits of screening for prostate cancer.  These groups include the American Urological Association, who recommend screening men beginning at age 50 and have a life expectancy of at least 10 years, and even earlier in African-American men or those who have a family history of prostate cancer.

The American Cancer Society has similar guidelines to the American Urological Association, although include a digital rectal exam with the PSA.  The National Comprehensive Cancer Network recommends using a PSA cutoff of 2.5 ng/mL, which is lower than the 4.0 ng/mL cutoff traditionally used.  Endorsement of prostate cancer screening also comes from the National Academy of Clinical Biochemistry, and all groups recommend that a positive PSA be repeated prior to prostate biopsy.

Recommendations for Screening


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