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PSA Standardization


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PSA Testing at Mayo

Slide 33

October 2009

At the Mayo Clinic, total and free PSA are performed on the Beckman Coulter DXI using the Hybritech calibration.  There is a Total PSA Screen which is used for screening purposes and a Total PSA Diagnostic which is useful for monitoring or diagnosing prostate cancer.  There is no difference between the total PSA used for screening or diagnostic purposes; however, Medicare does reimburse the tests differently based on the CPT code that is submitted.  Total and free PSA can also be measured together and a free to total ratio is reported only if the total PSA is between 2-10 ng/ml.  In the near future, we plan to move to a WHO-calibrated method and there are ongoing discussions about the strategy we will use.

PSA Testing at Mayo


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