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PSA Standardization

PSA Testing at Mayo

Slide 33

October 2009

At the Mayo Clinic, total and free PSA are performed on the Beckman Coulter DXI using the Hybritech calibration.  There is a Total PSA Screen which is used for screening purposes and a Total PSA Diagnostic which is useful for monitoring or diagnosing prostate cancer.  There is no difference between the total PSA used for screening or diagnostic purposes; however, Medicare does reimburse the tests differently based on the CPT code that is submitted.  Total and free PSA can also be measured together and a free to total ratio is reported only if the total PSA is between 2-10 ng/ml.  In the near future, we plan to move to a WHO-calibrated method and there are ongoing discussions about the strategy we will use.

PSA Testing at Mayo


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