Laboratory Diagnosis of HIV Infection

Reasons for Testing: Late vs. Early Testers

October 2009

When the CDC looked at the reason that these individuals come for HIV testing, we see this graph where most of them actually present very late in their HIV infection for testing because they became ill. Whereas, if we looked at those who came for early diagnostic testing, you can see that most of them came because their partners are at risk and were found to have HIV infection, and early diagnostic testing is defined as those who were tested more than 5 years before they developed AIDS. Whereas those who actually presented for late or early testing, very few of them were tested because of routine check-up, as indicated by the 2 bars in the red circle here. So, in the effort to reduce HIV transmission, we should increase our effort by promoting HIV testing in doing a routine check-up.

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• Introduction
• HIV Markers During Early Infection
• Assay-Defined HIV Detection Windows and Infection Periods
• Serologic Tests for HIV Infection in US
• Principle of Future Combined HIV Antigen-Antibody ELISAs
• Virology Tests for HIV Infection
• HIV Serologic Screening Algorithm
• HIV Rapid Serology Follow-up Algorithm
• Indeterminate HIV-1 Antibody Western Blot Results
• Rapid HIV Antibody Tests Licensed in US, 2009
• Predictive Value: Single Screening Test
• Rapid HIV Antibody Tests: Clinical Applications
• Follow-Up Testing of Reactive Rapid HIV-1 Antibody Tests Results
• Diagnostic HIV Testing in Infants
• Diagnostic HIV Testing in Infants
• Awareness of Serostatus Among People with HIV and Estimates of Transmission in US
• Reasons for Testing: Late vs. Early Testers
• 2006 US CDC Recommendations: Adults and Adolescents
• 2006 US CDC Recommendations: Adults and Adolescents
• 2006 US CDC Recommendations: Pregnant Women
• 2006 US CDC Recommendations: Pregnant Women
• Summary
• Questions?
• Disclosure