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The INR and FFP

Is This a Good Relationship with Regard to Transfusion Practice?



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Coagulation Tests and Invasive Procedures

Slide 7

December 2008

Why do people give FFP prior to invasive procedures? The rationale underlying these transfusions is that even a mildly elevated INR is associated with excessive bleeding in the setting of an invasive procedure and that an intervention is needed for safety.

The assumptions driving pre-procedural use of FFP are

  • The elevation of the PR/INR predicts bleeding in the setting of an invasive procedure.
  • This elevated PT/INR must be corrected in order to safely perform the procedure.
  • Pre-procedure administration of FFP will correct the prolonged clotting time result.

Prophylactic FFP transfusions prevent or minimize the excessive bleeding that would have occurred in the absence of such transfusions.

Coagulation Tests and Invasive Procedures

 


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