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The INR and FFP

Is This a Good Relationship with Regard to Transfusion Practice?


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Coagulation Tests and Invasive Procedures, cont.

Slide 11

December 2008

The safety of central vein cannulation in the setting of abnormal coagulation testing results has been evaluated in three studies from the 1990s. The largest of these studies was published in 1999. This was a prospective evaluation of 580 patients with INR 1.5 or higher who had central lines places. Eighty-three percent of these patients also had a platelet count below 150,000/μL. Major bleeding occurred in one patient following central line placement for an overall event rate of 0.2%. Furthermore, this event was found to be due to inadvertent arterial puncture, therefore it was a technical performance issue rather than bleeding due to abnormal coagulation.

Coagulation Tests, cont.


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