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Risk Stratification in Chronic Lymphocytic Leukemia

The Role of the Clinical Laboratory

ZAP-70 by Flow in CLL

Slide 17

November 2008

Here’s another example. Again, in the upper left histogram, quad stats are set based on 0.10% ZAP-70 positive B-cells. In the upper right histogram, one sees that the T-cells and NK-cells are appropriately positive.

In the lower left histogram, we see the patient of interest and indeed, in contrast to the previous patient, we see here if we take 62.5% divided by the total B-cell percentage, that we end up with 76% of the B-cells expressing ZAP-70, which would be interpreted as positive for this particular patient.

ZAP-70 by Flow in CLL


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