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Risk Stratification in Chronic Lymphocytic Leukemia

The Role of the Clinical Laboratory

CLL: Fragile Cells and Time to Treatment

Slide 10

November 2008

A very interesting observation by Nowakowski and colleagues was that the number of fragile cells was actually related to the time of treatment in these patients. Those cases with numerous fragile cells failed to reach a 50% treatment mark up to 12 years post-diagnosis, whereas those who had few fragile cells progressed more rapidly to treatment, i.e., reaching a 50% point at approximately 6 years.

Fragile Cells


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